In the article, the authors have stated that NOT ONLY is vitamin D2 less effective and has a shorter half life, but it also has a "nonphysiologic metabolism". This is a complicated way of saying that Vitamin D2 may not actually do the things that Vitamin D is actually supposed to do!
For example, one of the things that Vitamin d does is to bind to the 'Vitamin D Receptors' that are throughout the entire body. These Vitamin D Receptors are responsible for genes turning on or off in many disease states. If the VDR's are full of vitamin d then the genes are less likely to cause disease.
Yet, vitamin d2 only binds to these Vitamin D Receptors 40% as well as Vitamin D3. So, even if your Vitamin D Level is 'Normal', you are getting 60% less protection from the disease states that having a normal vitamin D level is supposed to protect you against!
So, it would be a great idea to print out 'The case against vitamin D2 as a vitamin supplement', take a highlighter pen, highlight the important parts and take the study to your doctor and ask him why he is choosing to use an inferior form of Vitamin D when your health is at stake.
Then, you might want to go get some Vitamin D 3 Supplements and ask him what dose of THOSE you should take in order to get the full benefits of having Vitamin D in the first place!
Kerri Knox, RN- The Immune Health Queen Functional Medicine Practitioner Easy Immune Health.com
Read the paper - will use D2 along with D3 by: Searching
Never a history of anxiety or depression, always an A type personality...go til I dropped.
Maintained a good attitude and pretty much just happy even with stressful jobs, a passel of kids and a bad marriage.
Have had fatigue, brain fog, lack of motivation, weird depression, and anxiety - first full blown anx attack at 44!
Have had some strange immune issues, shingles, guttate psoriasis along the way.
After a perfect storm of back inj and surgery(NSAIDS damaged my digestive system, GERD (PPI's further damaged digestive system)
Started feeling no energy, no motivation, sad, no concentration. Hard to do anything other than bare minimal survival.
Tested for so much. Finally got to the endocrinologist (wonderful!)
Low Vit D(22)and Zinc a little low.
Prescribed daily D3 and 50,000 iu D2 once per week for 4 weeks.
Also got a script for Phentermine to help with fatigue.
After holding off weeks, took both today. I read the article and although I see that is not as effective all round, hence the super high dose, and that the half life is terrible, it makes sense to give my poor body a boost and couple it with the appropriate D3 10,000 per day for the long term (along with Vit A, and at least 266 mg MAGNESIUM citrate)
Thoughts?
Except for the fact... by: Kerri Knox, The Immune Queen
Except for the fact that physiologically, Vitamin D2 is completely different and doesn't provide the protection from disease that Vitamin D does.
It's like having both a Ferrari and a beat up motor scooter that might break down at any minute right in front of you, and choosing to take the motor scooter because you 'want to get to the store'.
Well, both will get you to the store, but the Ferrari will get you there with a lot more perks. Why would you chose the broken down motor scooter (Vitamin D2) for the 'boost' when you can simply take the same dose of Vitamin D3 and get the same 'boost' in blood levels, but with all the benefits of the disease-prevention that Vitamin D3 gives you.
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