Looking for dosage instructions for Vitamin B12 Deficiency

by Jenn
(Hershey, PA)

I have self diagnosed myself with a vitamin B12 deficiency as my family doctor seems rather uneducated in this particular area. I do have the 1298 MTHFR genetic mutation, that I've read can cause a deficiency. I am always fatigued, sleep poorly, have difficulty concentrating, mild depression and anxiety, and have been diagnosed with regional myofascial pain syndrome, which I interpret as a diagnosis that says "I realize you have chronic neck/shoulder/upper back pain, but I have no idea why."

I started taking Jarrow Formulas Methyl B12 5000 mcg lozenges about 5 weeks ago. I haven't really noticed a difference over all. I may have felt better on days that I've taken 2 at the same time. I've read that the sublingual supplements are better absorbed. So, my questions are:

1. Should I try a different brand with a sublingual version?

2. Would a higher dose once a day be as beneficial as a 5000 mcg dose twice a day?

3. Are they better taken on an empty stomach or with meals?

4. Why are they in mcg dosages as opposed to mg in doses greater than 1 mg?

Your advice is greatly appreciated!

Jenn